cover
Contact Name
Editor PSR
Contact Email
article@farmasi.ui.ac.id
Phone
+62-21-27608403
Journal Mail Official
psr@farmasi.ui.ac.id
Editorial Address
3rd Floor, A Building, Rumpun Ilmu Kesehatan Kampus Baru UI Depok, 16424, Indonesia
Location
Kota depok,
Jawa barat
INDONESIA
Pharmaceutical Sciences and Research (PSR)
Published by Universitas Indonesia
ISSN : 24072354     EISSN : 24770612     DOI : https://doi.org/10.7454/psr
Core Subject :
Aims Pharmaceutical Sciences and Research (PSR), an international, peer-reviewed, open access, and official journal from Faculty of Pharmacy, Universitas Indonesia, aims to disseminate research results and findings in Pharmaceutical Sciences and Practices. Major area of interest is natural products in drug discovery and development. We also consider other areas related to pharmaceutical sciences and practices. PSR publishes content in English language to promote the sharing of knowledge to international scholars. PSR publish 5 types of articles: 1. Original article 2. Case report 3. Case series 4. Review article 5. Mini review article Scope Researches in Pharmaceutical Sciences and Practices which are covered by PSR are within these subject areas: - Pharmacognosy and Phytochemistry - Pharmaceutical Chemistry - Pharmaceutical Technology - Pharmaceutical Biotechnology - Clinical Pharmacy - Pharmacology-Toxicology - Social and Administrative Pharmacy, including Pharmacoeconomy
Arjuna Subject : -
Articles 7 Documents
Search results for , issue "Vol. 1, No. 2" : 7 Documents clear
Arah dan Perkembangan Liposome Drugs Delivery Systems Jufri, Mahdi
Majalah Ilmu Kefarmasian Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Since the dicovery of liposome or lipid vesicles derived from self limiting enclosed lipid bilayer upon hydration, liposome drug delivery systems have played a significant role in formulation of potent drugs to improve therapeutics. Currenlty most of these liposome formulation are designed to reduced toxicity and to some extent increase accumulation at the target site(s) in a the number of clinical application. The current pharmaceutical preparations of liposome based therapeutics stem from our understanding of lipid drug interactions and the liposome disposition mechanism including the inhibition of rapid clearance of liposome by controlling size , charge and surface hydration.
Uji Mutagenisitas dan Anti Kanker Ekstrak Aseton Dan N-Heksana Dari Kulit Batang Sesoot (Garcinia picrorrhiza Miq.) Radji, Maksum; Sumiati, Atiek; Indani, Nuning
Majalah Ilmu Kefarmasian Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Mutagenicity and anti-mutagenicity of the acetone and n-hexane extracts of Garcinia picrorrhiza Miq.bark have been studied by Ames method using Salmonella typhimurium TA 97, TA 98 TA 100, TA 102, dan Escherichia coli WP2. The results showed that the two extracts had a positive effect. It can be concluded that the acetone and n-hexane extracts of Garcinia picrorrhiza Miq. bark have anticancer activity.
Metode Penetapan Kadar Meloxicam Dalam Darah Manusia In Vitro Secara Kromatografi Cair Kinerja Tinggi Harmita, Harmita; Mansur, Umar; Firnando, Firnando
Majalah Ilmu Kefarmasian Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Until nowadays study of drug profile inside body (pharmacokinetic) and its development is still an interesting topic under pharmaceutical service. Development of an accurate analysis method for small quantity of drug in blood is an important step, HPLC method usually recommended for this purpose. Observation in studying the optimal method to analyze drug in human blood by using internal standard has been done for meloxicam, a new generation of NSAID. Two things has been focused to this observation, finding an ideal internal standard for meloxicam and testing the recovery of meloxicam in blood sample by in vitro. Coefficient of distribution of many samples (piroxicam, trimetropim, caffeine, salisilamid) gives caffeine as recommended internal standard for meloxicam. The recovery test gives 83,58% ± 3,802%, 74,37% ± 0,711%, 82,14% ± 1,937% for analysis meloxicam in human blood without internal standard; and 41,58% ± 1,108%, 61,60% ± 1,049%, 56,88% ± 0,478% for analysis meloxicam in human blood within internal standard.
Mikroenkapsulasi Propanolol Hidroklorida Dengan Penyalut Etil Selulosa Menggunakan Metoda Penguapan Pelarut Sutriyo, Sutriyo; Djajadisastra, Joshita; Novitasari, Adilla
Majalah Ilmu Kefarmasian Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Propranolol hydrochloride is antihypertension agent that has a short biological half life of 2-6 hours. Microcapsules of propranolol hydrochloride are prepared by solvent evaporation method using ethylcellulose as a wall material with the drug-polymer ratio 1:1, 1:2, and 1:3 for sustained release oral delivery. The microcapsules were then evaluated by particle size distribution analysis, shape and morphology (SEM), drug content, and dissolution studies. In vitro dissolution was studied using the dissolution apparatus II (paddle) with chloride buffer (pH 1,2) dan phosphate buffer (pH 6,8) medium. The drug-polymer ratio have an important influence on drug release from microcapsules where the increase of polymer cause the higher drug release inhibition.
Gambaran Pelaksanaan Standar Pelayanan Farmasi Di Apotek DKI Jakarta Tahun 2003 Purwanti, Angki; Harianto, Harianto; Supardi, Sudibjo
Majalah Ilmu Kefarmasian Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

The service orientation of clinical pharmacy and community have been changed from focusing only managing the medicine as commodity to comprehensive service based on pharmaceutical care. Refer to that basic, ISFI with the cooperation of Min- istry of Health establish Standard of Pharmaceutical Service in Pharmacy. The stan- dard is aimed to ensure the service quality and shall be implemented in all Pharma- cies. The purpose of the study is to have an implementation overview Standard of Pharmaceutical Service in Pharmacy and the results may used for establishing the phase of implementation Standard of Pharmaceutical Service in Pharmacy. This study is a descriptive study, the data were compiled by using a question- naire, as respondents. Compiled data consist of pharmacy’s basic data, pharmacist’s basic data, implementation of non prescription drug’s service (section I), KIE’s ser- vice (section II), prescription drug’s service (section III) and management of medi- cine (section IV). The average score of implementation of section I is 60.18 (not good), section II is 31.84 (worse), section III is 64.22 (not good) , section IV 87.84 (good) and the overall average from section I to IV is 61.02 (not good)
Uji Efek Antiinflamasi Fraksi Air Daun Mahkota Dewa (Phaleria macrocarpa (Shecff.) Boerl.) terhadap Tikus Putih (Rattus norvegicus L.) Eff, Aprilita Rina Yanti; Dewanti, Ema; Adelina H, Melisha
Pharmaceutical Sciences and Research Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Inflammation occurs as the attempt of body to inactivate organisms that attack the body, removing irritants and regulate tissue repair. One of the medicinal plants used empirically as antiinflammation is the leaf of Mahkota Dewa (Phaleria macrocarpa (Schecff.) Boerl). This study investigated the effect of anti-inflammatory water fraction of leaf Mahkota Dewa using oedema induction method with caragenin in rat. Water fraction of Mahkota Dewa was given at the dose 0.5 g/kg BW ,1 g/kg BW and 2 g/kg BW. Sodium diclofenac was used as a positive control and CMC as negative control. The result showed water fractions of three doses can inhibit inflammation at 27.35%, 18.58%, and 20.17%, respectively. The water fraction at the dose 0.5 g/kgBW showed the largest percentage of oedema inhibition compared to other treatment groups.
Aktivitas Penghentian Pendarahan Luar Ekstrak Etanol Daun Berenuk (Crescentia cujete L) Secara In-Vivo Kusuma, Anjar Mahardian; Sulistyo, Adri Nurrakhmat; Susanti, Susanti; Sabikis, Sabikis
Pharmaceutical Sciences and Research Vol. 1, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Crescenti cujete L. or better known as calabash is a plant that thrives in Indonesia. Calabash has a great potential as an herbal remedy, but there is only some scientific research conducted on this plant, one of which is antibacterial against Bacillus subtilis and Escerichia coli on 2006 by Susanti. The method in this research was an experimental activities of the cessation external bleeding with 3 dose variation of calabash leaf extract 80%, 60%, and 40% by counting the bleeding time at base of the tail in mice. As a result, all groups of external bleeding cessation activities have better outcomes than negative controls (p < 0,05).

Page 1 of 1 | Total Record : 7